The information down below lists described adverse reactions, rated utilizing the next frequency classification:

Maintain VALTOCO in a secure spot to prevent misuse and abuse. Selling or giving away VALTOCO might harm Other people and is versus the regulation. Inform your Health care provider For those who have abused or been depending on Liquor, prescription medicine, or street drugs. It is not regarded if VALTOCO is Secure and effective in kids below 6 yrs of age. IMPORTANT Protection Information and facts

oxcarbazepine will lower the extent or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

Examine the Instructions to be used for in-depth details about the correct approach to use VALTOCO. Use VALTOCO particularly as prescribed from the Health care service provider. Your Health care provider will let you know: What seizure clusters are Precisely exactly how much VALTOCO to present When and how to give VALTOCO How to proceed When you give VALTOCO In case the seizures never stop or There's a alter in breathing, habits, or problem that concerns you You need to have VALTOCO with you just in case you need to have to regulate your seizure clusters.

mitotane decreases amounts of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Mitotane is a solid inducer of cytochrome P-4503A4; observe when coadministered with CYP3A4 substrates for achievable dosage changes.

If this drug is useful for an extended time frame, lab and/or professional medical tests (including liver purpose tests, entire blood count) may be performed if you are getting this medication. Retain all healthcare and lab appointments.

Dihydrocodeine is surely an here opioid analgesic agent utilized for the management of soreness severe ample to call for an opioid analgesic and for which alternative remedies are insufficient.

“Close to this identical time, while, I became aware about VALTOCO. I preferred that it had been a straightforward-to-use quick-use seizure medication. It’s also much less uncomfortable or embarrassing due to the fact I don’t need to rely upon somebody else to administer it rectally.

larotrectinib will improve the stage or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Solid or average CYP3A4 inhibitors may reduce amount of diazepam elimination, thus rising adverse reactions to diazepam.

apalutamide will lower the extent or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with drugs which can be CYP3A4 substrates may lead to lessen exposure to those medications.

stiripentol will lessen the level or outcome of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep track of Carefully. Consider reducing the dose of CYP2C19 substrates, if adverse reactions are skilled when administered concomitantly with stiripentol.

A Patient Info Leaflet (PIL) is usually a doc A part of the package deal of a medication that gives certain information regarding that medication and its use. It consists of specifics of dose and administration of your medicine, warnings and precautions and prospective Unwanted side effects.

Benzodiazepines, like VALTOCO, can increase intraocular stress in sufferers with glaucoma. VALTOCO could possibly be used in patients with open-angle glaucoma only if they are obtaining proper therapy.

Call a healthcare provider straight away if you have any of such symptoms, especially if they are new, even worse, or be concerned you: